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Course
Our course reviews central human physiology topics. Using short, bite-sized video lessons, learn the basic physiology. Then practice what you learned with quiz questions, including review of a clinical case, teaching you how to not only understand but apply what you've learned to real-world problems.
Topics
Course Topics
• Negative feedback and homeostasis
• Positive feedback
• Clinical Case: Type II Diabetes
• Ion concentrations and gradients
• Diffusion and passive transport
• Active transport
• Osmosis
• Clinical case intro: Excess water consumption
• Tonicity: Hypotonic, Isotonic, Hypertonic
• Tonicity of Common Intravenous Fluids
• Clinical Case: Hypotonic Solution Mistakenly Given to Patient
• Autocrine, Paracrine, Endocrine Cell Signaling.
• Signal Transduction Pathways
• G-Protein Coupled Receptors (GPCR)
• Clinical case: Beta-Blocker Drugs Control Heart Rate Via GPCRs.
• Resting Membrane Potential
• Nernst Equation
• Graded Potentials
• Action Potentials
• Clinical Case: Hypokalemia and Ionic Imbalances
• Clinical Case: Multiple Sclerosis and Demyelination
• Skeletal Fiber Anatomy
• Excitation-Contraction Coupling
• Properties of Skeletal Contraction: Tetanus, Ideal Length, Excitation-Contraction Delay
• Clinical Case: Tetanus and Rigor Mortis
• Heart Anatomy
• Cardiac Muscle Contraction: Excitation-Contraction Coupling
• Cardiac Cycle: Electrical Conduction System, ECG, and Cardiac Rhythm
• Clinical Case: Abnormal ECGs Including Ventricular Fibrillation and Ventricular Tachycardia.
• Parasympathetic Nervous System
• Sympathetic Nervous System
• Autonomic and Antagonistic Control of Organs
• Clinical case: Vagal maneuvers to control heart rate and rhythm.
• Blood Pressure Gradient Drives Blood Flow
• Parasympathetic and Sympathetic Nervous System Overview
• Autonomic Nervous System Control of Blood Pressure
• Heart Rate, Stroke Volume, Vessel Diameter Changes
• Respiratory Anatomy Review
• Gas Exchange: External and Internal Respiration
• Gas Transport: oxygen and carbon dioxide transport
• Spirometry, Lung Volumes, and Lung Capacities
• Clinical case: Asthma and Chronic Obstructive Pulmonary Disease.
• Chemical signaling using hormones
• Hypothalamic-Pituitary Axis
• Insulin and glucagon
• Clinical case: Type 1 and 2 Diabetes
• Overview of Kidney Anatomy: Glomerulus, Nephron, and Kidney
• Glomerular Filtration and Urine Production
• Absorption and Secretion Through the Nephron
• Kidneys Role in Blood Pressure Regulation
• Clinical Case: Diabetes Insipidus and Excessive Urine Production
• Ideal Blood pH
• Le Chatelier's Principle
• Respiratory Control of pH
• Renal Control of pH
• Clinical Case: Metabolic Alkalosis Triggered by Diarrhea Decreases Breathing Rate
• Gamete Formation
• Male Reproductive System
• Female Reproductive System
• Menstrual Cycle and Pregnancy
• Contraceptives
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